This antibody specifically binds to DR3 receptors has uses in the prevention, detection, diagnosis, treatment or amelioration of a disease or disorder, especially inflammatory and autoimmune diseases, such as Crohn's disease, Inflammatory Bowel Disease, Multiple Sclerosis.
Endotoxin: < 1 EU/mg
Host Species: Human
Type: Humanized antibody
Specificity: Human
Clone: 11H08_H1
Applications: Agonist, Block, FC, FuncS
Related Disease: Crohn's disease, colitis, Inflammatory Bowel Disease, arthritis, asthma, Multiple Sclerosis, atherosclerosis, and allergic disorders
Application Notes: This antibody has been reported for use in Agonist, Blocking, Flow Cytotoxicityometry, Functional Assay.
Alternative Names: TNFRSF25; tumor necrosis factor receptor superfamily, member 25; DR3; TR3; DDR3; LARD; APO-3; TRAMP; WSL-1; WSL-LR; TNFRSF12; tumor necrosis factor receptor superfamily member 25; protein WSL-1; death receptor beta; apoptosis inducing receptor; apoptosis-inducing receptor AIR; apoptosis-mediating receptor DR3; apoptosis-mediating receptor TRAMP; death domain receptor 3 soluble form; lymphocyte-associated receptor of death; tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
Gene ID: 8718
UniProt ID: Q93038