Mouse anti-Hla mAb (8B7) - 100ug

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    Full name: Mouse anti-Staphylococcal Alpha Hemolysin Toxin mAb (8B7)

    Immunogen: Polypeptide sequence of Staphylococcus alphahemolysin targeting the N terminus of the mature toxin.

    Description: Mouse monoclonal antibody (mAb) reactive to full
    length Staphylococcus aureus alpha-hemolysin (alpha-toxin). The
    antibody detects the antigen produced by S. aureus strains in
    Western Blotting and ELISA and neutralizes the hemolytic
    activity of the toxin.

    Supplied: 100 µg is supplied in PBS at a concentration of 1.68 mg/mL. 

    Purification: Antibody is purified using immobilized protein A

    Relevance: The antibody can be used for detection and neutralization of alpha-toxin produced by virulent strains of S. aureus.


    Recommended Dilutions: Optimal use dilution should be determined for each individual application.


    Storage: 2-3 weeks +4C, -20C long term

    Cross Reactivity: This antibody does not appear to cross react with Staphylococcal enterotoxin B (SEB), rLukS-PV or rLukF-PV based on historical ELISA data. As with most antibodies, this antibody interacts with Protein A in S. aureus culture supernatant via the Fc region.

    Toxin neutralization: Using a rabbit RBC lysis assay, EC50 of this antibody for neutralization of 0.3 ug/mL of alpha-toxin was
    determined to be 0.676 ug/mL.