A readily soluble, specific and sensitive substrate for chymotrypsin and human pancreatic elastase. It is also hydrolyzed by cathepsin G and chymase. Furthermore it is the standard substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins, which belong to the group of peptidyl prolyl cis-trans isomerases (PPIases). Thus, Suc-AAPF-pNA has been used for an uncoupled protease-free assay of PPIase activity.
CAS Number: 70967-97-4
Molecular weight: 624.65
Sum Formula: C₃₀H₃₆N₆O₉
Storage Temperature: < -15°C
Synonyms: SAAPNA
One Letter code: Suc-AAPF-pNA
Source: Synthetic
Old Product Number: L-1400
| Substrates |
|---|
| Cathepsin G |
| Chymotrypsin |
| Pancreatic Elastase |
| Chymase |
| Brachyurin |
| Peptidylprolyl Isomerase |